CMA | B2397

CMA is a murine-selective STING agonist (Kd = 3.5 μM). It directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route. CMA triggers type I IFN response in murine macrophages. However, does not activate human STING signaling.

CMA is a murine-selective STING agonist (Kd = 3.5 μM). It directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route. CMA triggers type I IFN response in murine macrophages. However, does not activate human STING signaling.

B2397 | CMA DataSheet

Alternate Name/Synonyms: 10-carboxymethyl-9-acridanone, Cridanimod, 9-Oxo-10(9H)-acridineacetic acid

Appearance: Yellow solid

Formulation:

CAS Number: 38609-97-1

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₅H₁₁NO₃

Molecular Weight: 253.25

Cell-Permeable?: True

Purity: ≥98% by HPLC

Solubilities: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A murine-selective STING agonist

MDL Number:

PubChem CID: 38072

SMILES: C1=CC=C2C(=C1)C(=O)C3=CC=CC=C3N2CC(=O)O

InChi: InChI=1S/C15H11NO3/c17-14(18)9-16-12-7-3-1-5-10(12)15(19)11-6-2-4-8-13(11)16/h1-8H,9H2,(H,17,18)

InChi Key: UOMKBIIXHQIERR-UHFFFAOYSA-N