CNIH3 Antibody (N-term) [APR04222G]

CNIH3 Antibody (N-term) [APR04222G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This CNIH3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-44 amino acids from the N-terminal region of human CNIH3.

Cellular Localisation: Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein Note=Also localizes to the cell membrane of extrasynaptic sites (dendritic shafts, spines of pyramidal cells) .

Molecular Weight: 18976

Clone: Polyclonal

Gene Name: CNIH3

Gene ID: 149111

Function: Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs) . Promotes their targeting to the cell membrane and synapses and modulates their gating properties by regulating their rates of activation, deactivation and desensitization.

Summary: Tissue Location: Expression is up-regulated in dorsolateral prefrontal cortex of patients with schizophrenia (postmortem brain study) .

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Protein cornichon homolog 3, CNIH-3, Cornichon family AMPA receptor auxiliary protein 3, CNIH3