CNO Antibody (Center) [APR04584G]

CNO Antibody (Center) [APR04584G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This CNO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 114-143 amino acids from the Central region of human CNO.

Cellular Localisation: Cytoplasm.

Molecular Weight: 23351

Clone: Polyclonal

Gene Name: BLOC1S4

Gene ID: 55330

Function: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking.

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Biogenesis of lysosome-related organelles complex 1 subunit 4, BLOC-1 subunit 4, Protein cappuccino homolog, BLOC1S4, CNO