CNTF, human recombinant | 4017

CNTF (Ciliary Neurotrophic Factor) is a potent neural factor that was originally characterized as a survivability factor for chick ciliary neurons in vitro. CNTF has also been shown to promote survivability and differentiation of other neuronal cell types. Recombinant human CNTF is a 22.9 kDa protein containing 200 amino acid residues

4017 | CNTF human recombinant DataSheet

Biomolecule/Target: CNTF

Synonyms: HCNTF, CNTF, Ciliary Neurotrophic Factor.

Alternates names: Bone morphogenetic protein 5, BMP-5, BMP5, MGC34244

Taglines: A potent neural factor promoting survivability and differentiation of neuronal cell types.

NCBI Gene ID #: 653

NCBI Gene Symbol: BMP5

Gene Source: Human

Accession #: P22003

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: 98%

Assay #2: HPLC

Endotoxin Level: <0.1 ng/g

Activity (Specifications/test method): N/A

Biological activity: The ED as determined by the dose-dependent induction of alkaline phosphatase production with ATDC5 chondrogenic cells is typically 0.3-3 µg/ml.

Results: < 2 ng/ml

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 31.0 kDa

Concentration: N/A

Appearance: Lyophilized protein

Physical form description: Sterile filtered and lyophilized without additives

Reconstitution Instructions: Reconstitute to a concentration of 0.1-1.0 mg/ml in HO containing BSA (50 ug BSA per 1 ug of protein). This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20° for future use.

Amino acid sequence: N/A