CNTFR polyclonal Antibody | BS7424

CNTFR polyclonal Antibody | BS7424 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB 1:400 - 1:2000

Background: This gene encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in this gene may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for this gene.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CNTFR polyclonal Antibody detects endogenous levels of CNTFR protein.

Molecular Weight: ~41 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Ciliary neurotrophic factor receptor alpha; Ciliary neurotrophic factor receptor; Ciliary neurotrophic factor receptor subunit alpha; CNTF receptor subunit alpha; CNTFR Alpha; CNTFR; CNTFR-alpha; CNTFR_HUMAN;

Immunogen: Recombinant full length Human CNTFR.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: