COL13A1 Antibody (N-term) [APR15515G]

COL13A1 Antibody (N-term) [APR15515G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This COL13A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53-81 amino acids from the N-terminal region of human COL13A1.

Cellular Localisation: Cell membrane; Single-pass type II membrane protein Cell junction, synapse, postsynaptic cell membrane

Molecular Weight: 69950

Clone: Polyclonal

Gene Name: COL13A1 (HGNC:2190)

Gene ID: 1305

Function: Involved in cell-matrix and cell-cell adhesion interactions that are required for normal development. May participate in the linkage between muscle fiber and basement membrane. May play a role in endochondral ossification of bone and branching morphogenesis of lung. Binds heparin. At neuromuscular junctions, may play a role in acetylcholine receptor clustering (PubMed:26626625) .

Summary: Tissue Location: Widely expressed in both fetal and adult ocular tissues (at protein level) . In the eye, expression is accentuated in the ciliary muscle, optic nerve and the neural retina. In early placenta, localized to fibroblastoid stromal cells of the placental villi, to endothelial cells of developing capillaries and to cells of the cytotrophoblastic columns. Also detected in large decidual cells of the decidual membrane and to stromal cells of the gestational endometrium, but not in the epithelial cells in the endometrial glands Isoform 10: Expressed in muscle (PubMed:26626625)

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, IHC-P

Dilution: WB--1:1000 IHC-P--1:100~500

Synonyms: Collagen alpha-1 (XIII) chain, COLXIIIA1, COL13A1 (HGNC:2190)