COL2A1 Monoclonal Antibody | E-AB-70295

COL2A1 Monoclonal Antibody | E-AB-70295 | Gentaur UK, US & Europe Distribution

Type: Monoclonal Antibody

Synonyms: Alpha 1 type II collagen, Alpha-1 type II collagen, AOM, Cartilage collagen, Chondrocalcin, CO2A1, COL11A3, Col2a1, Collagen II alpha 1 polypeptide, SEDC

Application: IHC

Reactivity: Mouse, Rat

Host: Mouse

Isotype: IgG

Reserch Areas: Cancer, Signal Transduction, Stem Cells

Background: This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene.

Concentration: 2.6 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein corresponding to Mouse collagen II

Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Purification Method: Affinity purification

Dilution: IHC 1:300-1:1000

Clone: 2F12D3

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A