Colchicine | 1519

Inhibitor of microtubules by specific binding to tubulin. Antimitotic tool used in cell division studies; Antibiotic; anti-inflammatory; therapeutic agent. Induce apoptosis in PC-12 cells and cerebellar granule cells.

Colchicine is an inhibitor of microtubules by specific binding to tubulin.

1519 | Colchicine DataSheet

Alternate Name/Synonyms: N-​[(7S)-​1,​2,​3,​10-​ tetramethoxy-​9-​oxo-​5,​6,​7,​9-​tetrahydrobenzo​[a]​heptalen-​ 7-​yl]​acetamide

Appearance: White solid

Formulation: N/A

CAS Number: 64-86-8

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₂H₂₅NO₆

Molecular Weight: 399.4

Cell-Permeable?: Yes

Purity: >99%

Solubilities: DMSO and H₂O (10 mg/ml)

Handling: Protect from light and air

Country of Origin: USA

Tag Line: A mirotubule inhibitor

MDL Number: MFCD00078484

PubChem CID: 6167

SMILES: CC(=O)NC1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)OC)OC

InChi: InChI=1S/C22H25NO6/c1-12(24)23-16-8-6-13-10-19(27-3)21(28-4)22(29-5)20(13)14-7-9-18(26-2)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)/t16-/m0/s1

InChi Key: IAKHMKGGTNLKSZ-INIZCTEOSA-N