749

Collagen II Mouse Monoclonal Antibody (1H1) | ABM40364

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SKU:
749-ABM40364
Availability:
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NULL254.00 - NULL691.00

Description

Collagen II Mouse Monoclonal Antibody (1H1) | ABM40364 | Gentaur UK, US & Europe Distribution

Immunogen: Synthetic Peptide of Collagen II

Product Category: Protein

Application: Protein General Reagents

Product Type: Primary Antibody

Host: Mouse

Reactivity: Human, Mouse, Rat

Application: IHC-P

Application Note: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:200) .

Clonality: Monoclonal

Isotype: Mouse IgG1

Formulation: Liquid solution

Kit Component: N/A

Concentration: 1 mg/ml

Storage Buffer: PBS, pH 7.4, containing 0.02% Sodium Azide as preservative and 50% Glycerol.

Storage Instructions: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Shipping Condition: Gel pack with blue ice.

Background: COL2A1 (collagen type II alpha 1 chain) encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in COL2A1 are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for COL2A1.

Alternative Names: Collagen alpha-1 (II) chain; Alpha-1 type II collagen

Precaution: The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

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