Columbianadin | B1334

Columbianadin (CBN) is a coumarin-type compound and one of the main bioactive constituents of the underground part of the herb, Angelica pubescens. Columbianadin has calcium-channel blocking function, can inhibit depolarization induced Ca2+ uptake in rat pituitary GH3 cells.

Columbianadin (CBN) is a coumarin-type compound and one of the main bioactive constituents of the underground part of the herb, Angelica pubescens. Columbianadin has calcium-channel blocking function, can inhibit depolarization induced Ca2+ uptake in rat pituitary GH3 cells.

B1334 | Columbianadin DataSheet

Alternate Name/Synonyms: 2-[(8S)-2-oxo-8,9-dihydrofuro[2,3-h]chromen-8-yl]propan-2-yl (Z)-2-methylbut-2-enoate

Appearance: Solid

Formulation: N/A

CAS Number: 5058-13-9

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C19H20O5

Molecular Weight: 328.36

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A calcium-channel blocker and inhibits depolarization induced Ca2+ uptake

MDL Number: MFCD07781426

PubChem CID: 6436246

SMILES: CC=C(C)C(=O)OC(C)(C)C1CC2=C(O1)C=CC3=C2OC(=O)C=C3

InChi: 1S/C19H20O5/c1-5-11(2)18(21)24-19(3,4)15-10-13-14(22-15)8-6-12-7-9-16(20)23-17(12)13/h5-9,15H,10H2,1-4H3/b11-5-/t15-/m0/s1

InChi Key: JRIBPWOXWIRQOQ-GHAIFCDISA-N