Complement C3c, Human Plasma | P1271

Complement C3 (C3) is the most abundant component of the complement system, with levels in human plasma of ~1.2-1.5 mg/ml. It is central to the activation of both the classical and alternative complement pathways, both of which lead to the proteolytic processing of C3 to C3a and C3b. C3 exists as a heterodimer with molecular masses of 115 kDa and 75 kDa, although it is readily processed to create C3a, C3b or C3c depending on the processed state

P1271 | Complement C3c Human Plasma DataSheet

Biomolecule/Target: C3c

Synonyms: Compelement C3c

Alternates names: Bone morphogenetic protein 5, BMP-5, BMP5, MGC34244

Taglines: A potent chemotactic factor for neutrophilsin chronic inflammation

NCBI Gene ID #: 653

NCBI Gene Symbol: BMP5

Gene Source: Human

Accession #: P22003

Recombinant: No

Source: Human Plasma

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: N/A

Activity (Specifications/test method): N/A

Biological activity: The ED as determined by the dose-dependent induction of alkaline phosphatase production with ATDC5 chondrogenic cells is typically 0.3-3 µg/ml.

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 31.0 kDa

Concentration: N/A

Appearance: Liquid

Physical form description: In PBS, pH 7.4

Reconstitution Instructions: Reconstitute to a concentration of 0.1-1.0 mg/ml in HO containing BSA (50 ug BSA per 1 ug of protein). This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20° for future use.

Amino acid sequence: N/A