Complement Component C1q, Human Serum | P1721

Complement subcomponent C1q is composed of three polypeptide chains (A, B, and C). C1q associates with C1r and C1s to set up the first component of the serum complement system. Activation of the complement system is induced by interaction with the Fc regions of IgG or IgM antibodies within immune complexes, enhancing the ability of those antibodies and cells of the immune system to attack pathogens. C1q deficiency is associated with lupus and glomerulonephritis.

P1721 | Complement Component C1q, Human Serum DataSheet

Biomolecule/Target :

Synonyms: C1q; C1QA; C1QB; C1QC; C1QG; Complement Component 1, Q Subcomponent

Alternates names: C1q; C1QA; C1QB; C1QC; C1QG; Complement Component 1, Q Subcomponent

Taglines: A critical component of the classical complement system

NCBI Gene ID #: Chain A - 712; Chain B - 713; Chain C - 714

NCBI Gene Symbol:

Gene Source: Human

Accession #: Chain A - P02745; Chain B - P02746; Chain C - P02747

Recombinant: False

Source: Human serum

Purity by SDS-PAGE: ≥ 96% by SDS-PAGE

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Unit Definition:

Molecular Weight: 410 kDa

Concentration:

Appearance: Lyophilized protein

Physical form description: Lyophilized powder

Reconstitution Instructions: Reconstitute to desired concentration in sterile deionized water.

Amino acid sequence:

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans