Complement fragment 3c Polyclonal Antibody | BS65951

Complement fragment 3c Polyclonal Antibody | BS65951 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat,Dog,Pig,

Application: WB,

Application Range: WB=1:500-2000

Background: C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Complement fragment 3c Polyclonal Antibody detects endogenous levels of Complement fragment 3c protein.

Molecular Weight: 183 kD

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: AHUS5; acylation-stimulating protein cleavage product; ARMD9; ASP; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; C3; CO3_HUMAN; Complement C3; Complement C3c alpha' chain fragment 2; Complement C3c; Complement component 3; Complement component C3; Complement factor 3; CPAMD1.

Immunogen: KLH conjugated synthetic peptide derived from human Complement C3c alpha' chain fragment 1:1051-1200/1663

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: affinity purified by Protein A

Pathway: