Connexin 50 Antibody (N-term) [APR11267G]

Connexin 50 Antibody (N-term) [APR11267G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This Connexin 50 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 99-130 amino acids from the N-terminal region of human Connexin 50.

Cellular Localisation: Cell membrane; Multi-pass membrane protein {ECO:0000250|UniProtKB:P55917}. Cell junction, gap junction

Molecular Weight: 48229

Clone: Polyclonal

Gene Name: GJA8

Gene ID: 2703

Function: Structural component of eye lens gap junctions (PubMed:18006672, PubMed:19756179) . Gap junctions are dodecameric channels that connect the cytoplasm of adjoining cells. They are formed by the docking of two hexameric hemichannels, one from each cell membrane (By similarity) . Small molecules and ions diffuse from one cell to a neighboring cell via the central pore (PubMed:18006672, PubMed:19756179) .

Summary: Tissue Location: Eye lens..

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Gap junction alpha-8 protein, Connexin-50, Cx50, Lens fiber protein MP70, GJA8