Cox-4 (C-terminus) monoclonal Antibody | MB0102

Cox-4 (C-terminus) monoclonal Antibody | MB0102 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human,Mouse,Rat,Monkey,Goat,Hamster

Application: WB FC ICC IP

Application Range: WB: 1:1000~5000 ICC: 1:100~200 IP: 1:50~200 FC: 1:50~100

Background: Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain.It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane.The complex consists of 13 mitochondrial- and nuclear-encoded subunits.The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities.The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex.This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme.It is located at the 3´ of the NOC4 (neighbor of COX4) gene in a head-to-head orientation,and shares a promoter with it.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: This Antibody detects endogenous levels of COX4 and does not cross-react with related proteins

Molecular Weight: Predicted band size:17KDa Observed band size:17KDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Cytochrome c oxidase subunit 4 isoform 1, mitochondrial; Cytochrome c oxidase polypeptide IV; Cytochrome c oxidase subunit IV isoform 1; COX IV-1; COX4I1; COX4

Immunogen: Synthetic peptide, corresponding to the C-terminus of Human Cox-4.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: Warburg Effect,Insulin &Glucose Signaling,Glutamine Metabolism,