CP-424174 | B2531

CP-424,174 is a cytokine release inhibitory drug (CRID) that inhibits the post-translational processing and secretion of IL-1β in response to LPS and ATP in human monocytes. Also indirectly inhibits NLRP3.

CP-424,174 is a cytokine release inhibitory drug (CRID) that inhibits the post-translational processing and secretion of IL-1β in response to LPS and ATP in human monocytes. Also indirectly inhibits NLRP3.

B2531 | CP-424174 DataSheet

Alternate Name/Synonyms: N-[[[4-Chloro-2,6-bis(1-methylethyl)phenyl]amino]carbonyl]-3-(1-hydroxy-1-methylethyl)benzenesulfonamide, CP424174, CP 424174

Appearance: White solid

Formulation:

CAS Number: 210825-31-3

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₂H₂₉ClN₂O₄S

Molecular Weight: 452.99

Cell-Permeable?: True

Purity: ≥98% by HPLC

Solubilities: >40 mg/ml in Ethanol, >40 mg/ml in DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: An inhibitor of IL-1β post-translational processing

MDL Number:

PubChem CID: 9911728

SMILES: CC(C)C1=CC(=CC(=C1NC(=O)NS(=O)(=O)C2=CC=CC(=C2)C(C)(C)O)C(C)C)Cl

InChi: InChI=1S/C22H29ClN2O4S/c1-13(2)18-11-16(23)12-19(14(3)4)20(18)24-21(26)25-30(28,29)17-9-7-8-15(10-17)22(5,6)27/h7-14,27H,1-6H3,(H2,24,25,26)

InChi Key: YRSBLSHMKVQWHP-UHFFFAOYSA-N