CP-673451 | B1337

CP-673451 is a potent inhibitor of PDGFR with IC50 value of 10 nM and 1 nM for PDGFR-α and PDGFR-β, respectively.

CP-673451 is a potent inhibitor of PDGFR with IC50 value of 10 nM and 1 nM for PDGFR-α and PDGFR-β, respectively.

B1337 | CP-673451 DataSheet

Alternate Name/Synonyms: 1-[2-[5-(2-methoxyethoxy)benzimidazol-1-yl]quinolin-8-yl]piperidin-4-amine

Appearance: Solid

Formulation: N/A

CAS Number: 343787-29-1

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C24H27N5O2

Molecular Weight: 417.51

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: >20.9 mg/ml in DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent inhibitor of PDGFR

MDL Number: MFCD11100329

PubChem CID: 10158940

SMILES: COCCOC1=CC2=C(C=C1)N(C=N2)C3=NC4=C(C=CC=C4N5CCC(CC5)N)C=C3

InChi: 1S/C24H27N5O2/c1-30-13-14-31-19-6-7-21-20(15-19)26-16-29(21)23-8-5-17-3-2-4-22(24(17)27-23)28-11-9-18(25)10-12-28/h2-8,15-16,18H,9-14,25H2,1H3

InChi Key: DEEOXSOLTLIWMG-UHFFFAOYSA-N