223

CPEB1 Antibody | 4687

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SKU:
223-4687-GEN
£682.00 - £1,294.00

Description

CPEB1 Antibody | 4687 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: CPEB1 antibody was raised against a 14 amino acid synthetic peptide from near the amino terminus of human CPEB1.
The immunogen is located within amino acids 50 - 100 of CPEB1.

Research Area: Homeostasis

Tested Application: E, WB

Application: CPEB1 antibody can be used for detection of CPEB1 by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in rat samples. All other applications and species not yet tested.

Specificiy: N/A

Positive Control 1: Cat. No. 1463 - Rat Brain Tissue Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: CPEB1 Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: CPEB1 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: CPEB1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: CPEB1 Antibody: CEBP, CPEB, CPEB-1, CPE-BP1, hCPEB-1, Cytoplasmic polyadenylation element-binding protein 1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: CPEB1 Antibody: CPEB1 is an RNA binding protein that contains an RNA-recognition motif and a zinc finger-containing region found in a wide range of vertebrates and invertebrates. CPEB1 forms the nucleus of a complex of factors that regulate poly (A) elongation and promotes polyadenylation-induced translation. CPEB1 mediates many diverse biological processes such as germ cell development, cell division and senescence, and synaptic plasticity. Recently, it was discovered that CPEB1 is involved in beta-catenin mRNA translation and cell migration in astrocytes as well as regulating hypoxia-inducible factor (HIF) -1 expression, demonstrating the wide range of processes in which CPEB1 plays a role. At least four isoforms of CPEB1 are known to exist.

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