CPI-0610 | B1201

CPI-0610 is a potent, selective BET (bromodomain and extra terminal family of proteins) inhibitor and inhibits BRD4-BD1 with IC₅₀ of 39 nM. It potentially demonstrates anti-neoplastic activity by binding acetylated lysine recognition motifs on the bromodomain of BET proteins, thus preventing the interaction of BET proteins and acetylated histone peptides.

CPI-0610 is a potent, selective BET (bromodomain and extra terminal family of proteins) inhibitor and inhibits BRD4-BD1 with IC₅₀ of 39 nM. It potentially demonstrates anti-neoplastic activity by binding acetylated lysine recognition motifs on the bromodomain of BET proteins, thus preventing the interaction of BET proteins and acetylated histone peptides.

B1201 | CPI-0610 DataSheet

Alternate Name/Synonyms: (S)-2-(6-(4-chlorophenyl)-1-methyl-4H-benzo[c]isoxazolo[4,5-e]azepin-4-yl)acetamide

Appearance: White Solid

Formulation: N/A

CAS Number: 1380087-89-7

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₀H₁₆ClN₃O₂

Molecular Weight: 365.82

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO(>3 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent, and selective BET (bromodomain and extra terminal family of proteins) inhibitor

MDL Number: N/A

PubChem CID: 76534645

SMILES: CC1=NOC2=C1C3=CC=CC=C3C(=NC2CC(=O)N)C4=CC=C(C=C4)Cl

InChi: InChI=1S/C20H16ClN3O2/c1-11-18-14-4-2-3-5-15(14)19(12-6-8-13(21)9-7-12)23-16(10-17(22)25)20(18)26-24-11/h2-9,16H,10H2,1H3,(H2,22,25)

InChi Key: GCWIQUVXWZWCLE-UHFFFAOYSA-N