CPT2 polyclonal Antibody | BS90329

CPT2 polyclonal Antibody | BS90329 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Application: WB ICC/IF IHC

Application Range: WB:1:500-1:1,000 ICC:1:50-1:200 IHC:1:50-1:200

Background: The mitochondrial β-oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase (CPT) I (outer membrane and detergent labile) and II (inner membrane and detergent stable), together with carnitine carrier. CPTI catalyzes the first reaction in the transport of long-chain fatty acids from the cytoplasm to the mitochondrion, a rate-limiting step in beta-oxidation. Two types of CPTI are known, the liver (CPTIA) and muscle (CPTIB) isoforms. The muscle type protein is specially expressed in heart and skeletal muscle. Membrane-bound CPTI, but not CPTII, is inhibited reversibly by malonyl-coenzyme A (CoA) . Unlike CPTII, CPTI requires membrane integrity for catalytic function. In addition, glutamic acid 3 and histidine 5 are necessary for malonyl CoA inhibition and binding to liver CPTI, but not for catalytic activity.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: CPT2 polyclonal Antibody detects endogenous levels of CPT2 protein.

Molecular Weight: 74 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: CPT II, CPT2, Carnitine O palmitoyltransferase 2, Carnitine O palmitoyltransferase 2 mitochondrial, Carnitine O-palmitoyltransferase 2, Carnitine palmitoyltransferase 2, Carnitine palmitoyltransferase II, CPT 1, CPT 2, CPT II, CPT1, CPT2, CPT2, CPTASE, CPTII, IIAE4, mitochondrial,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: