CPUY192018 | B3230

CPUY192018 is a potent inhibitor of the Keap1-Nrf2 PPI protein-protein interaction. CPUY192018 displays cytoprotective effects by enhancing the Nrf2-ARE regulated antioxidant system and diminishes the LPS-induced inflammatory response by hindering the ROS-mediated activation of the NF-κB pathway.

CPUY192018 is a potent inhibitor of the Keap1-Nrf2 PPI protein-protein interaction. CPUY192018 displays cytoprotective effects by enhancing the Nrf2-ARE regulated antioxidant system and diminishes the LPS-induced inflammatory response by hindering the ROS-mediated activation of the NF-κB pathway.

B3230 | CPUY192018 DataSheet

Alternate Name/Synonyms: 1,4-Bis[Carboxymethyl-(4-methoxy-benzenesulfonyl)-amino]-naphthalene

Appearance: Crystalline solid

Formulation:

CAS Number: 1567836-15-0

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₈H₂₆N₂O₁₀S₂

Molecular Weight: 614.64

Cell-Permeable?: True

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A potent inhibitor of the Keap1-Nrf2 PPI protein-protein interaction

MDL Number:

PubChem CID: 73330369

SMILES: COC1=CC=C(C=C1)S(=O)(=O)N(CC(=O)O)C2=CC=C(C3=CC=CC=C32)N(CC(=O)O)S(=O)(=O)C4=CC=C(C=C4)OC

InChi: InChI=1S/C28H26N2O10S2/c1-39-19-7-11-21(12-8-19)41(35,36)29(17-27(31)32)25-15-16-26(24-6-4-3-5-23(24)25)30(18-28(33)34)42(37,38)22-13-9-20(40-2)10-14-22/h3-16H,17-18H2,1-2H3,(H,31,32)(H,33,34)

InChi Key: KWSIQJUNYMMCTB-UHFFFAOYSA-N