CPXM2 polyclonal Antibody | BS61150

CPXM2 polyclonal Antibody | BS61150 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: Members of the M14 metallocarboxypeptidase protein family serve many diverse functions and are divided into three subfamilies based on structure, function and amino acid sequence similarity. Belonging to the N/E subfamily, CPXM2 (Inactive carboxypeptidase-like protein X2) is a 756 amino acid protein that contains a F5/8 type C domain and is secreted. Most members of the N/E subfamily contain several domains, including an active carboxypeptidase domain and signal peptide and are thought to function mostly in mediating protein-protein interactions and/or protein-membrane interactions, thereby targeting the protein to specific locations within the secretory pathway. CPXM2 is a unique member of this subfamily in that it does not appear to exhibit any enzymatic activity due to lack of several active-site residues that are present in the catalytic domain of other members of the N/E subfamily. Expression of the closely related protein CPXM is regulated during osteoclastogenesis, suggesting that CPXM may play a role in osteoclast differentiation.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CPXM2 polyclonal Antibody detects endogenous levels of CPXM2 protein.

Molecular Weight: ~ 86 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Inactive carboxypeptidase-like protein X2; CPXM2

Immunogen: A synthetic peptide corresponding to residues in Human CPXM2.

Conjugate: N/A

Modification: N/A

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: N/A