CREB Blocking Peptide | 3360RBP

3360RBP | CREB Blocking Peptide DataSheet

Antibody Target: CREB

Accession #: EDL98880

Gene ID: 81646

Appearance: Colorless liquid

Concentration: 0.5 mg/ml

Formulation: 50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal.

Short Description: 50 ug Blocking Peptide for CREB polyclonal antibody (3360R-100).

Application & Usage: Transcription factor CREB binds the cAMP response element (CRE) and activates transcription in response to a variety of extracellular signals including neurotransmitters, hormones, membrane depolarization, and growth or neurotrophic factors. Protein kinase A and the calmodulin-dependent protein kinase CaMKII stimulate CREB phosphorylation at Ser133, a key regulatory site controlling transcriptional activity. Phosphorylation at Ser133 is also mediated by p44/42 MAP kinase, p90RSK, p38 MAP kinase and MSK1. CREB appears to play an important role in learning and memory in both flies and mice.

Research Use: For Rersearch Use Only! Not to be used in humans.

Western Blot (WB): Verified

Handling: The peptide solution should be gently mixed before use.