CREM Antibody (C-term) [APR15587G]

CREM Antibody (C-term) [APR15587G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This CREM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 287-314 amino acids from the C-terminal region of human CREM.

Cellular Localisation: Nucleus.

Molecular Weight: 37006

Clone: Polyclonal

Gene Name: CREM (HGNC:2352)

Gene ID: 1390

Function: Transcriptional regulator that binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. Isoforms are either transcriptional activators or repressors. Plays a role in spermatogenesis and is involved in spermatid maturation (PubMed:10373550) .

Summary: Tissue Location: Expressed in testes (round spermatids) (at protein level) . Isoform 14 is the major activator form in testes

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, FC

Dilution: WB--1:1000 FC--1:10~50

Synonyms: cAMP-responsive element modulator, Inducible cAMP early repressor, ICER, CREM