CRHR2 Antibody | 33-056

CRHR2 Antibody | 33-056 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: A recombinant protein fragment from the N-terminal portion of human CRHR2 was used as the immunogen for this antibody (1) .

Research Area: Neuroscience, Growth Factors

Tested Application: WB

Application: Western blot: 0.5-2 ug/ml
Provided assay concentrations are suggestions only, CRHR2 antibody titration may be required for optimal results.

1. This antibody will detect the alpha (411 AA) , beta (438 AA) and gamma (397 AA) isoforms of CRHR2.

Specificiy: N/A

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: Protein A affinity chromatography

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.1 mg/ml BSA and 0.05% sodium azide

Concentration: 0.5 mg/mL

Storage Condition: Aliquot and Store at -20˚C. Avoid freez-thaw cycles.

Alternate Name: Corticotropin-releasing factor receptor 2, CRF-R-2, CRF-R2, CRFR-2, Corticotropin-releasing hormone receptor 2, CRH-R-2, CRH-R2, CRHR2, CRF2R, CRH2R

User Note: Optimal dilutions for each application to be determined by the researcher

BACKGROUND: CHCR2, or Corticotropin releasing hormone receptor 2, is a receptor for CRH (corticotropin-releasing hormone) , a neurotransmitter secreted by the hypothalamus in response to stress. There are three major isoforms of CHCR2: alpha, beta and gamma, differing in their N-terminus amino acid sequence. Isoform beta and gamma are expressed in the brain, with gamma expression highest in the septum and hippocampus, while alpha is expressed in the peripheral tissues of the brain.