CRM1 polyclonal Antibody | BS90332

CRM1 polyclonal Antibody | BS90332 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Application: WB ICC IF IHC FC

Application Range: WB:1:500 ICC:1:50-1:200 IHC:1:50-1:100 FC:1:50-1:100

Background: Protein transport across the nucleus is a selective, multistep process involving several cytoplasmic factors. Proteins must be recognized as import substrates, dock at the nuclear pore complex and translocate across the nuclear envelope in an ATP-dependent fashion. Two cytosolic factors centrally involved in the recognition and docking process are the karyopherin alpha1 and karyopherin beta1 subunits. p62 glycoprotein is a nucleoporin that is not only involved in the nuclear import of proteins, but also the export of nascent mRNA strands. NTF2 (nuclear transport factor 2) interacts with nucleoporin p62 as a homodimer composed of two monomers, and may be an obligate component of functional p62. CRM1 has been shown to be an export receptor for leucine-rich proteins that contain the nuclear export signal (NES) .

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: CRM1 polyclonal Antibody detects endogenous levels of CRM1 protein.

Molecular Weight: 123 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Exp1, XPO1, CRM1, Chromosome region maintenance 1 protein homolog, CRM 1, CRM1 homolog, DKFZp686B1823, emb, Exp 1, Exp1, Exportin 1, Exportin-1, Exportin1, XPO 1, xpo1, XPO1,

Immunogen: Recombinant protein within C terminal human CRM1.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: