CRMP1 Polyclonal Antibody | E-AB-12333

CRMP1 Polyclonal Antibody | E-AB-12333 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Collapsin response mediator protein 1, CRMP 1, CRMP-1, Crmp1, Dihydropyrimidinase like 1, Dihydropyrimidinase related protein 1, Dihydropyrimidinase-related protein 1, DPYL1, DPYSL1, DRP 1, DRP-1, DRP1, ULIP-3, Ulip3, Unc-33-like phosphoprotein 3

Application: WB, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Neuroscience, Signal Transduction

Background: Collapsin response mediator protein 1, encoded by theCRMP1gene, is a humanproteinof theCRMP family. This gene encodes a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system. The encoded protein is thought to be a part of the semaphorin signal transduction pathway implicated in semaphorin-induced growth cone collapse during neural development. Alternative splicing results in multiple transcript variants. CRMP1 mediates reelin signaling in cortical neuronal migration. Mice deficient in CRMP1 exhibit impaired long-term potentiation and impaired spatial learning and memory. CRMP1 gene overlaps with another gene called EVC. CRMP1 has been shown to interact with DPYSL2.

Concentration: 0.4 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human CRMP1

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:1000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 62 kDa

Molecular Weight(Observed): N/A