CRMP2 polyclonal Antibody | BS90334

CRMP2 polyclonal Antibody | BS90334 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Application: WB ICC IHC

Application Range: WB:1:1,000-1:5,000 ICC:1:50-1:200 IHC:1:50-1:200

Background: Collapsin response mediator proteins (CRMPs), including CRMP-1 (DRP-1), CRMP-2 (DRP-2 or TOAD64), CRMP-3 (DRP-4), CRMP-4 (DRP-3) and CRMP-5 (DRP-5), mediate signal transduction after exposure of neural cells to the axon guidance molecule Semaphorin 3A (SEMA3A) /collapsin. CRMPs are present in the developing cerebral cortex and neocortical neurons and are responsive to SEMA3A. In the adult brain, the expression of CRMPs is dramatically downregulated. However, they remain expressed in structures that retain their capacity for differentiation and plasticity. CRMP-2 is involved in axonal growth and guidance. The human CRMP-2 gene maps to 8p21.2, a chromosomal region that has been previously shown to have a significant linkage to schizophrenia and to several deficit symptoms of schizophrenia.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Specificity: CRMP2 polyclonal Antibody detects endogenous levels of CRMP2 protein.

Molecular Weight: 62 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: DRP-2, CRMP-2, ULIP-2, DPYSL2, CRMP2, ULIP2, Collapsin response mediator protein 2, Collapsin response mediator protein, Collapsin response mediator protein hCRMP 2, CRAM, CRMP 2, CRMP-2, CRMP2, DHPRP 2, DHPRP2, Dihydropyrimidinase 2, Dihydropyrimidinase like 2, Dihydropyrimidinase like 2 long form, Dihydropyrimidinase related protein 2, Dihydropyrimidinase-related protein 2, DPYL 2, DPYL2, DPYL2, DPYSL 2, Dpysl2, DRP-2, DRP2, Musunc 33, Musunc33, N2A3, TOAD 64, TOAD64, ULIP 2 protein, ULIP-2, Ulip2, Unc-33-like phosphoprotein 2,

Immunogen: Recombinant protein with Human CRMP2 aa 100-300.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Protein affinity purified.

Pathway: