CRTAM Polyclonal Antibody | E-AB-10260

CRTAM Polyclonal Antibody | E-AB-10260 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: CD355, Class I MHC restricted T cell associated molecule, Class-I MHC-restricted T-cell-associated molecule, CRTAM, CRTAM, Cytotoxic and regulatory T cell molecule, Cytotoxic and regulatory T-cell molecule

Application: WB, IHC, ELISA

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Immunology

Background: The CRTAM gene is upregulated in CD4 (see MIM 186940)-positive and CD8 (see CD8A; MIM 186910)-positive T cells and encodes a type I transmembrane protein with V and C1-like Ig domains. Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo.

Concentration: 0.3 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human CRTAM

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 45 kDa

Molecular Weight(Observed): Refer to Figures