Cryptotanshinone | 2429

Cryptotanshinone is a natural product isolated from the roots of Salvia miltiorrhiza Bunge that displays a variety of biological activities. Displays antitumor activity by inhibition of STAT3 (IC₅₀ = 4.6 µM). Also displays antibacterial and anti-inflammatory activity and acts as an antidiabetes and antiobesity agent via activation of AMP-activated protein kinase (AMPK). Also inhibits acetylcholinesterase (AChE) (IC₅₀ = 4.09 μM) and reduction in Aβ peptide generation.

Cryptotanshinone is a natural product isolated from the roots of Salvia miltiorrhiza Bunge that displays a variety of biological activities. Displays antitumor activity by inhibition of STAT3 (IC₅₀= 4.6 µM).

2429 | Cryptotanshinone DataSheet

Alternate Name/Synonyms: 1,2,6,7,8,9-Hexahydro-1,6,6-trimeth​yl[1,2-b]furan-10,11-dione

Appearance: Orange solid

Formulation: N/A

CAS Number: 35825-57-1

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₉H₂₀O₃

Molecular Weight: 296.36

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (~ 5 mg/ml)

Handling: Protect from light and air

Country of Origin: USA

Tag Line: A STAT3 inhibitor

MDL Number: MFCD07636810

PubChem CID: 160254

SMILES: CC1COC2=C1C(=O)C(=O)C3=C2C=CC4=C3CCCC4(C)C

InChi: InChI=1S/C19H20O3/c1-10-9-22-18-12-6-7-13-11(5-4-8-19(13,2)3)15(12)17(21)16(20)14(10)18/h6-7,10H,4-5,8-9H2,1-3H3/t10-/m0/s1

InChi Key: GVKKJJOMQCNPGB-JTQLQIEISA-N