CSF1 polyclonal Antibody | BS60697

CSF1 polyclonal Antibody | BS60697 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: The macrophage colony-stimulating factor (M-CSF), also designated CSF-1, was originally discovered in serum, urine and other biological fluids as a factor that can stimulate the formation of macrophage colonies from bone marrow hematopoietic progenitor cells. M-CSF is a homodimeric cytokine that is produced by fibroblasts, epithelial cells, bone marrow stromal cells, osteoblasts, keratinocytes, macrophages, T cells and B cells. M-CSF is a glycoprotein required for the proliferation and differentiation of mononuclear phagocytes, including osteoclasts. M-CSF has also been identified as an important mediator of the inflammatory response and can regulate the release of proinflammatory cytokines from macrophages. M-CSF exerts its pleiotropic effects by binding to a single type of high affinity cell surface receptor that is encoded by the c-Fms proto-oncogene.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CSF1 polyclonal Antibody detects endogenous levels of CSF1 protein.

Molecular Weight: ~ 70 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Macrophage colony-stimulating factor 1; CSF-1; M-CSF; MCSF; Lanimostim

Immunogen: A synthetic peptide corresponding to residues in Human CSF1

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: