CSF1R-IN-1 | B3300

CSF1R-IN-1, is a potent CSF1R inhibitor (IC50 of 0.5 nM). CSF1R plays an important role in the recruitment and differentiation of tumor-associated macrophages (TAM).

CSF1R-IN-1, is a potent CSF1R inhibitor (IC50 of 0.5 nM). CSF1R plays an important role in the recruitment and differentiation of tumor-associated macrophages (TAM).

B3300 | CSF1R-IN-1 DataSheet

Alternate Name/Synonyms: BUN49048 5-(1-methyl-1H-pyrazol-4-yl)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)nicotinamide

Appearance: Crystalline solid

Formulation:

CAS Number: 2095849-04-8

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₅H₂₀F₃N₅O₂

Molecular Weight: 479.46

Cell-Permeable?: TRUE

Purity: ≥98%

Solubilities: DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A CSF1R inhibitor

MDL Number:

PubChem CID: 137333440

SMILES: CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC=C2)C(F)(F)F)NC(=O)C3=CN=CC(=C3)C4=CN(N=C4)C

InChi: InChI=1S/C25H20F3N5O2/c1-15-6-7-21(31-23(34)16-4-3-5-20(9-16)25(26,27)28)10-22(15)32-24(35)18-8-17(11-29-12-18)19-13-30-33(2)14-19/h3-14H,1-2H3,(H,31,34)(H,32,35)

InChi Key: BMEXIUCHJUGPRB-UHFFFAOYSA-N