CSGALNACT1 Antibody (Center) [APR15609G]

CSGALNACT1 Antibody (Center) [APR15609G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This CSGALNACT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 192-220 amino acids from the Central region of human CSGALNACT1.

Cellular Localisation: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein

Molecular Weight: 61294

Clone: Polyclonal

Gene Name: CSGALNACT1 (HGNC:24290)

Gene ID: 55790

Function: Transfers 1, 4-N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of glucuronic acid (GlcUA) . Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains. Important role in chondroitin chain biosynthesis in cartilage formation and subsequent endochondral ossification (PubMed:11788602, PubMed:12163485, PubMed:12446672, PubMed:17145758, PubMed:31705726) . Moreover, is involved in the metabolism of aggrecan (By similarity) .

Summary: Tissue Location: Ubiquitous, with the highest levels in placenta, thyroid, bladder, prostate and adrenal gland. Detected at low levels in the other tissues examined.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, IHC-P

Dilution: WB--1:1000 IHC-P--1:100~500

Synonyms: Chondroitin sulfate N-acetylgalactosaminyltransferase 1, CsGalNAcT-1, Chondroitin beta-1, 4-N-acetylgalactosaminyltransferase 1, Beta4GalNAcT-1, CSGALNACT1, CHGN, GALNACT1