Csk (phospho-S364) polyclonal Antibody | BS4673

Csk (phospho-S364) polyclonal Antibody | BS4673 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: C terminal Src kinase (CSK) is a non receptor protein tyrosine kinase. One of its major functions is to specifically phosphorylate a conserved C terminal tyrosine of Src family kinases thereby down regulating their kinase activity. CSK is expressed ubiquitously as a protein of approximately 50 KDa in cytosol, but a fraction distributes to lipid rafts due to interaction with the lipid raft associated protein PAG (CSK binding protein) .

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Csk (phospho-S364) polyclonal Antibody detects endogenous levels of Csk protein when phosphorylated at Ser364.

Molecular Weight: ~ 50 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Tyrosine-protein kinase CSK; C-Src kinase; Protein-tyrosine kinase CYL; CSK

Immunogen: Synthetic phosphopeptide derived from human Csk around the phosphorylation site of Serine 364.

Conjugate: Unconjugated

Modification: Phosphorylation

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: Regulation of Actin Dynamics,Tumor Angiogenesis,Regulation of Microtubule Dynamics,Inhibition of Apoptosis,G Protein-coupled Receptors Signaling to MAPK Erk,