CSNK2A1 Antibody | 13-453

CSNK2A1 Antibody | 13-453 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-391 of human CSNK2A1 (NP_001886.1) .

Research Area: Apoptosis, Cell Cycle, Immunology, Signal Transduction

Tested Application: WB, IHC, IF

Application: WB: 1:1000 - 1:4000
IHC: 1:50 - 1:200
IF: 1:50 - 1:100

Specificiy: N/A

Positive Control 1: SGC-7901

Positive Control 2: H460

Positive Control 3: HT-1080

Positive Control 4: BT-474

Positive Control 5: SW620

Positive Control 6: Mouse liver

Molecular Weight: Observed: 45kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: CSNK2A1, CK2A1, CKII, CKII alpha, CSNK2A3

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. It is involved in various cellular processes, including cell cycle control, apoptosis, and circadian rhythm. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. The protein encoded by this gene represents the alpha subunit. While this gene is found on chromosome 20, a related transcribed pseudogene is found on chromosome 11. Three transcript variants encoding two different proteins have been found for this gene.