CT-2584 | B1182

CT-2584 is a cytotoxic agent that alters phospholipid biosynthesis via inhibition of CTP:choline-phosphate cytidylyltransferase causing an increase in phosphatidylinositol will decreasing levels of phosphatidylcholine. The altered phospholipid metabolism caused by CT-2584 results in a loss of lamellar structure and membrane integrity (especially in mitochondria and endoplasmic reticulum). CT-2584 was active against a wide range of tumor cell lines including multi-drug resistant lines.

CT-2584 is a cytotoxic agent that alters phospholipid biosynthesis via inhibition of CTP:choline-phosphate cytidylyltransferase causing an increase in phosphatidylinositol will decreasing levels of phosphatidylcholine. The altered phospholipid metabolism caused by CT-2584 results in a loss of lamellar structure and membrane integrity (especially in mitochondria and endoplasmic reticulum). CT-2584 was active against a wide range of tumor cell lines including multi-drug resistant lines.

B1182 | CT-2584 DataSheet

Alternate Name/Synonyms: 1-(11-Dodecylamino-10-hydroxyundecyl)-3,7-dimethylxanthine methane sulfonate

Appearance: White solid

Formulation: N/A

CAS Number: 166981-13-1 (free base)

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: N/A

Molecular Formula: C₃₀H₅₅N₅O₃.CH3SO3H

Molecular Weight: 629.9

Cell-Permeable?: Yes

Purity: ≥98% by TLC

Solubilities: DMSO (~25 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: CTP:choline-phosphate cytidylyltransferase inhibitor

MDL Number: N/A

PubChem CID: 3081346

SMILES: CCCCCCCCCCCCNCC(CCCCCCCCCN1C(=O)C2=C(N=CN2C)N(C1=O)C)O

InChi: InChI=1S/C30H55N5O3/c1-4-5-6-7-8-9-10-13-16-19-22-31-24-26(36)21-18-15-12-11-14-17-20-23-35-29(37)27-28(32-25-33(27)2)34(3)30(35)38/h25-26,31,36H,4-24H2,1-3H3

InChi Key: MZNMZWZGUGFQJP-UHFFFAOYSA-N