CTDSP1 Antibody (Center) [APR15594G]

CTDSP1 Antibody (Center) [APR15594G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This CTDSP1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 96-130 amino acids from the Central region of human CTDSP1.

Cellular Localisation: Nucleus. Note=Colocalizes with RNA polymerase II

Molecular Weight: 29203

Clone: Polyclonal

Gene Name: CTDSP1

Gene ID: 58190

Function: Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.

Summary: Tissue Location: Expression is restricted to non-neuronal tissues. Highest expression in skeletal muscle, spleen, lung and placenta

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, Nuclear LIM interactor-interacting factor 3, NLI-IF, NLI-interacting factor 3, Small C-terminal domain phosphatase 1, SCP1, Small CTD phosphatase 1, CTDSP1, NIF3, NLIIF, SCP1