CTDSPL polyclonal Antibody | BS90339

CTDSPL polyclonal Antibody | BS90339 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB FC

Application Range: WB:1:500 FC:1:50-1:100

Background: Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells (By similarity) . Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Specificity: CTDSPL polyclonal Antibody detects endogenous levels of CTDSPL protein.

Molecular Weight: 31kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: CTDSP-like, NLI-interacting factor 1, hYA22, SCP3, Small CTD phosphatase 3, CTDSPL, C3orf8, NIF1, NIFL, SCP3, YA22, C3orf8, Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 3, CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like, CTD small phosphatase-like protein, CTDSL, CTDSP-like, Ctdspl, hYA22, N-like protein, NIF-like protein, NLI-interacting factor 1, Nuclear LIM interactor-interacting factor 1, Protein YA22, RB protein serine phosphatase from chromosome 3, RBSP3, SCP3, Small C-terminal domain phosphatase 3, Small CTD phosphatase 3,

Immunogen: Recombinant protein within human CTDSPL aa 50-300.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Protein affinity purified.

Pathway: