Ctip2 polyclonal Antibody | BS90342

Ctip2 polyclonal Antibody | BS90342 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB ICC IHC FC

Application Range: WB:1:1,000 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100

Background: Bcl-11a (CtIP-1, EVI9, B cell chronic lymphocytic leukemia (CLL) /lymphoma 11A) and Bcl-11b (CtIP-2, RIT1, B cell CLL/lymphoma 11B) genes play crucial roles in lymphopoiesis and influence the progression of hematopoietic malignancies. Disruption of the Bcl-11b locus is linked to T cell acute lymphoblastic leukemia, and the loss of heterozygosity in mice results in T cell lymphoma. Bcl-11 proteins are related C2H2 zinc-finger transcription factors that act as transcriptional repressors. Bcl-11b can interact with the metastasis-associated proteins MTA1 and MTA2 through the amino-terminal region. Bcl-11a is essential for postnatal development and normal lymphopoiesis. The Bcl-11a mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with Bcl-6.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: Ctip2 polyclonal Antibody detects endogenous levels of Ctip2 protein.

Molecular Weight: 100/110kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: BCL11B, ATL1 alpha, ATL1, ATL1 beta, ATL1 gamma, ATL1-delta, B cell CLL/lymphoma 11B/T cell receptor delta constant region fusion protein, B cell lymphoma/leukemia 11B, B-cell CLL/lymphoma 11B (zinc finger protein), B-cell CLL/lymphoma 11B, B-cell lymphoma/leukemia 11B, BC11B, BCL-11B, Bcl11b, BCL11B/TRDC fusion, COUP TF interacting protein 2, COUP-TF interacting protein 2, COUP-TF-interacting protein 2, Ctip 2, CTIP-2, CTIP2, hRIT1 alpha, hRit1, Radiation induced tumor suppressor gene 1, Radiation induced tumor suppressor gene 1 protein, Radiation-induced tumor suppressor gene 1 protein, Rit 1, Rit1, zinc finger protein hRit1 alpha, ZNF856B,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: