CTSC Polyclonal Antibody | E-AB-13113

CTSC Polyclonal Antibody | E-AB-13113 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: AI047818, CATC, CATC, Cathepsin C, Cathepsin J, CPPI, CTSC, Dipeptidyl peptidase 1, Dipeptidyl peptidase 1 light chain, Dipeptidyl peptidase I, Dipeptidyl peptidase I exclusion domain chain, Dipeptidyl peptidase I heavy chain, Dipeptidyl peptidase I light chain, Dipeptidyl transferase, DPP I, DPP-I, DPPI, EC 3.4.14.1, HMS, JP, JPD, MGC126959, PALS, PDON1, PLS

Application: WB, IHC, ELISA

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Cell Biology

Background: The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis.

Concentration: 1.2 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human CTSC

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 52 kDa

Molecular Weight(Observed): N/A