CUL4B Antibody | 14-584

CUL4B Antibody | 14-584 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-152 of human CUL4B (NP_003579.3) .

Research Area: Cell Cycle

Tested Application: WB, IP

Application: WB: 1:500 - 1:2000
IP: 1:50 - 1:200

Specificiy: N/A

Positive Control 1: LO2

Positive Control 2: SH-SY5Y

Positive Control 3: HeLa

Positive Control 4: Mouse brain

Positive Control 5: Mouse testis

Positive Control 6: Mouse liver

Molecular Weight: Observed: 110kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: Cullin-4B, CUL-4B, CUL4B, KIAA0695

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene.