Curvularin | 9694

Isolated from Penicillium sp. Displays cytotoxic, antifungal, anti-inflammatory, and antiprotozoal properties. Acts as a TGF-β signaling pathway inhibitor as well as inducible nitric oxide synthase (iNOS; NOSII) inhibitor. Also, inhibits cell division and acts as an acetylcholinesterase (AChE) inhibitor.

Isolated from Penicillium sp. Displays cytotoxic, antifungal, anti-inflammatory, and antiprotozoal properties. Acts as a TGF-β signaling pathway inhibitor as well as inducible nitric oxide synthase (iNOS; NOSII) inhibitor. Also, inhibits cell division and acts as an acetylcholinesterase (AChE) inhibitor.

9694 | Curvularin DataSheet

Alternate Name/Synonyms: (5S)-13,15-dihydroxy-5-methyl-4-oxabicyclo[10.4.0]hexadeca-1(12),13,15-triene-3,11-dione; FKI-1938; NSC 166071

Appearance: Off-white solid

Formulation: N/A

CAS Number: 10140-70-2

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₆H₂₀O₅

Molecular Weight: 292.33

Cell-Permeable?: Yes

Purity: ≥95% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: An anti-inflammatory, and antiprotozoal agent

MDL Number: MFCD09752718

PubChem CID: 119418

SMILES: CC1CCCCCC(=O)C2=C(C=C(C=C2CC(=O)O1)O)O

InChi: InChI=1S/C16H20O5/c1-10-5-3-2-4-6-13(18)16-11(8-15(20)21-10)7-12(17)9-14(16)19/h7,9-10,17,19H,2-6,8H2,1H3/t10-/m0/s1

InChi Key: VDUIGYAPSXCJFC-JTQLQIEISA-N