Description
CW069 is an allosteric inhibitor of the microtubule motor protein HSET that induces multipolar mitoses only in cells containing supernumerary centrosomes.
CW069 is an allosteric inhibitor of the microtubule motor protein HSET that induces multipolar mitoses only in cells containing supernumerary centrosomes.
Alternate Name/Synonyms: 5-Iodo-2-[[(2S)-1-oxo-3-phenyl-2-[(phenylmethyl)amino]propyl]amino]-benzoic acid
Appearance: Crystalline solid
Formulation: N/A
CAS Number: 1594094-64-0
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₃H₂₁IN₂O₃
Molecular Weight: 500.33
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (>35 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: An allosteric inhibitor of the microtubule motor protein HSET
MDL Number: N/A
PubChem CID: 73427517
SMILES: C1=CC=C(C=C1)C[C@@H](C(=O)NC2=C(C=C(C=C2)I)C(=O)O)NCC3=CC=CC=C3
InChi: InChI=1S/C23H21IN2O3/c24-18-11-12-20(19(14-18)23(28)29)26-22(27)21(13-16-7-3-1-4-8-16)25-15-17-9-5-2-6-10-17/h1-12,14,21,25H,13,15H2,(H,26,27)(H,28,29)/t21-/m0/s1
InChi Key: IRDIXDXDSUBHIU-NRFANRHFSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |