CWC22 Polyclonal Antibody | BS65685

CWC22 Polyclonal Antibody | BS65685 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep,

Application: IHC-P,

Application Range: IHC-P=1:100-500

Background: Spliceosomes are multi-protein complexes that are composed of snRNPs (small nuclear ribonucleoproteins) and a variety of associated protein factors, all of which work in concert to regulate the splicing of pre-mRNA, a critical step in the post-transcriptional regulation of gene expression. CWC22 (CWC22 spliceosome-associated protein), also known as NCM, fSAPb or EIF4GL, is a 908 amino acid nuclear protein and component of the spliceosome C complex. CWC22 is associated with the spliceosome prior to catalytic steps and remains associated throughout the reaction. Belonging to the CWC22 family, CW22 contains one MI domain and a MIF4G domain. The gene encoding CWC22 maps to human chromosome 2q31.3. As the second largest human chromosome, chromosome 2 makes up approximately 8% of the human genome and contains 237 million bases encoding over 1,400 genes.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CWC22 Polyclonal Antibody detects endogenous levels of CWC22 protein.

Molecular Weight: 105kD

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: CWC22; CWC22 spliceosome associated protein homolog (S. cerevisiae) ; CWC22 spliceosome associated protein homolog; CWC22_HUMAN; EIF4GL; fSAPb; Functional spliceosome associated protein b; KIAA1604; NCM; Nucampholin homolog; Pre-mRNA-splicing factor CWC22 homolog.

Immunogen: KLH conjugated synthetic peptide derived from human CWC22

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: affinity purified by Protein A

Pathway: