CXCL10/IP-10/CRG-2, human recombinant | 4277

Human Chemokine (C-X-C motif) ligand 10(CXCL10),also known as Interferon gamma-inducible protein-10 (IP-10), is a non-ELR chemokine secreted by various cell types including monocytes, endothelial cells and fibroblasts in response to IFN-. CXCL10 functions via chemokine receptor CXCR3. CXCL10 has been attributed to several roles, such as chemo-attraction for activated T-lymphocytes, inhibition of angiogenesis and antitumor activity.

4277 | CXCL10/IP-10/CRG-2 human recombinant DataSheet

Biomolecule/Target: CXCL-10

Synonyms: 10 kDa interferon gamma-induced protein, Gamma-IP10, IP-10, Small-inducible cytokine B10

Alternates names: Cartilage-derived morphogenetic protein-1, CDMP-1, LAP4, SYNS2, GDF-5, Radotermin, CDMP1, GDF5, Growth differentiation factor 5, BMP-14

Taglines: Chemoattractant for monocytes, T cells, NK cells, and dendritic cells

NCBI Gene ID #: 8200

NCBI Gene Symbol: GDF5

Gene Source: Human

Accession #: X80915

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: 95%

Assay #2: HPLC

Endotoxin Level: <0.1 ng/g (1 IEU/g)

Activity (Specifications/test method): N/A

Biological activity: The ED as determined by its ability to induce alkaline phosphatase production by ATDC-5 chondrogenic cells is 1-2 µg/ml.

Results: 0.02-0.06 g/ml

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 13.6 kDa

Concentration: N/A

Appearance: Lyophilized protein

Physical form description: Lyophilized from a 0.2 m filtered solution of 20 mM PB and 150 mM NaCl, pH 7.0.

Reconstitution Instructions: Reconstitute to a concentration of 0.1-1.0 mg/ml in HO containing BSA (50 mg BSA per 1 mg of protein). This solution can then be diluted into other aqueous buffers.

Amino acid sequence: N/A