CXCL16, Human Recombinant | 7130

CXCL16 is a member of the CXC chemokine family and signals through the CXCR6 receptor. CXCL16 may play a role in attracting lymphocyte subsets during inflammation and may facilitate certain immune responses. The chemokine domain of CXCL16 contains six cysteine residues including the four highly conserved cysteine residues characteristic of CXC chemokines. The CXCL16 gene codes for a 273 amino acid polypeptide, which includes a 29 amino acid cytoplasmic domain and transmembrane sequence containing approximately 20 amino acids. The extracellular portion of CXCL16 contains a chemokines domain and an extended C-terminal “mucin-like stalk” sequence. The extracellular domain contains 89 amino acid residues (86 a.a. residues for the murine homolog). Recombinant human CXCL16 is a 10.1 kDa protein containing 89 amino acid residues.

7130 | CXCL16 Human Recombinant DataSheet

Biomolecule/Target: CXCL16

Synonyms: SRPSOX

Alternates names: bone morphogenetic protein 10, BMP10, BMP 10

Taglines: Plays a role in attracting lymphocyte subsets during inflammation

NCBI Gene ID #: 27302

NCBI Gene Symbol: BMP10

Gene Source: Human

Accession #: O95393

Recombinant: Yes

Source: E. coli.

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: N/A

Assay #2: HPLC

Endotoxin Level: < 0.1 ng/g of protein (<1EU/g).

Activity (Specifications/test method): Determined by its ability to chemoattract human lymphocytes using a concentration range of 1.0-100.0 ng/ml.

Biological activity: The protein is biologically active as determined by its ability to induce alkaline phosphatase production by C2C12 cells. The ED is in the range of 0.3-3 µg/ml.

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 32 kDa

Concentration: N/A

Appearance: Lyophilized powder

Physical form description: Sterile filtered through a 0.2 micron filter. Lyophilized with no additives.

Reconstitution Instructions: Reconstitute to a concentration of 0.1-1.0 mg/ml in HO containing BSA (50 µg BSA per 1 µg of protein). This solution can then be diluted into other aqueous buffers

Amino acid sequence: N/A