CXCL17, human recombinant | 7345

Chemokine (C-X-C motif) ligand 17, also known as CXCL17, is a small cytokine belonging to the CXC chemokine family. CXCL17 is a 119 amino acid secreted protein that plays a role in angiogenesis. CXCL17 is expressed in skeletal muscle, trachea, lung, intestine and stomach, and is upregulated in duodenal mucosa of patients with acute cholera, as well as breast tumors. CXCL17 is considered a housekeeping chemokine for the movement of immature dendritic cells and non-activated blood monocytes into tissues, and is thought to be involved in the innate immune response. Recombinant human CXCL17 protein, fused to His-tag at N-terminus, was expressed in E.coli.

7345 | CXCL17 human recombinant DataSheet

Biomolecule/Target: CXCL17

Synonyms: Chemokine (C-X-C motif) ligand 17, Dcip1, DMC, MGC138300, UNQ473, VCC-1, VCC1

Alternates names: Chemokine (C-X-C motif) ligand 17, Dcip1, DMC, MGC138300, UNQ473, VCC-1, VCC1

Taglines: Involved in the innate immune response

NCBI Gene ID #: 20423

NCBI Gene Symbol: SHH

Gene Source: Human

Accession #: Q8C765

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGEs: 97%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: N/A

Activity (Specifications/test method): N/A

Biological activity: N/A

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 13.7 kDa (119 aa, 22-119 aa + His Tag), confirmed by MALDI-TOF.

Concentration: 0.25 mg/ml

Appearance: Liquid

Physical form description: 0.25 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea and 10% glycerol.

Reconstitution Instructions: N/A

Amino acid sequence: MGSSHHHHHH SSGLVPRGSH MSSLNPGVAR GHRDRGQASR RWLQEGGQEC ECKDWFLRAP RRKFMTVSGL PKKQCPCDHF KGNVKKTRHQ RHHRKPNKHS RACQQFLKQC QLRSFALPL