CXCR3 polyclonal Antibody | BS65534

CXCR3 polyclonal Antibody | BS65534 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat,Dog,Pig,Cow,Rabbit,Guinea Pig,

Application: FCM

Application Range: Flow-Cyt=2ug/Test not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

Background: This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant) . Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716) . [provided by RefSeq, Jun 2011].

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CXCR3 polyclonal Antibody detects endogenous levels of CXCR3 protein.

Molecular Weight: ~40kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: CXC-R3; Interferon-inducible protein 10 receptor; IP-10 receptor; CKR-L2; CD183 antigen; G protein-coupled receptor 9; C-X-C Chemokine receptor; CD183; CXC Motif Receptor 3; CKRL2; CMKAR3; G Protein Coupled Receptor 9; GPR9; IP10; IP10R; MIGR; CXCR3_HUMAN.

Immunogen: KLH conjugated synthetic peptide derived from mouse CXCR3:301-367/367 

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: affinity purified by Protein A

Pathway: