CYB5R3 monoclonal Antibody | MB62961

CYB5R3 monoclonal Antibody | MB62961 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Monkey, Dog

Application: FC, IHC, WB

Application Range: WB 1:200~500, IHC 1:150, FLOW 1:100

Background: This gene encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in this gene cause methemoglobinemias. [provided by RefSeq]

Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: cytochrome b5 reductase 3

Molecular Weight: 34.1 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: B5R; DIA1

Immunogen: Full length human recombinant protein of human CYB5R3 (NP_000389) produced in HEK293T cell.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A