CYBA Antibody | 56-245

CYBA Antibody | 56-245 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Homology: N/A

Immunogen: This CYBA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 117-145 amino acids from the C-terminal region of human CYBA.

Research Area: Cancer, Cell Cycle, Immunology, Obesity

Tested Application: WB, IF

Application: For WB starting dilution is: 1:1000
For IF starting dilution is: 1:10~50

Specificiy: N/A

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: 21 kDa

Validation: N/A

Isoform: N/A

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Clonality: Polyclonal

Clone: N/A

Isotype: Rabbit Ig

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.

Concentration: batch dependent

Storage Condition: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: Cytochrome b-245 light chain, Cytochrome b (558) alpha chain, Cytochrome b558 subunit alpha, Neutrophil cytochrome b 22 kDa polypeptide, Superoxide-generating NADPH oxidase light chain subunit, p22 phagocyte B-cytochrome, p22-phox, p22phox, CYBA

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: Cytochrome b is comprised of a light chain (alpha) and a heavy chain (beta) . This gene encodes the light, alpha subunit which has been proposed as a primary component of the microbicidal oxidase system of phagocytes. Mutations in this gene are associated with autosomal recessive chronic granulomatous disease (CGD) , that is characterized by the failure of activated phagocytes to generate superoxide, which is important for the microbicidal activity of these cells.